Self-destruct TB vaccine shows promise in boosting safety, efficacy
1 day ago · The BCG vaccine, widely used in countries with high tuberculosis prevalence, primarily protects children against severe forms of the disease, such as tuberculous meningitis and miliary tuberculosis.
New, Safer, TB Vaccine with BCG "Kill Switch" Protects Mice and …
20 hours ago · Intravenous BCG vaccine with a built-in kill-switch was found to be at least as effective as regular tuberculosis vaccine in protecting monkeys against infection.
Revolutionary TB Vaccine Protects, Then Safely Self-Destructs
20 hours ago · Mouse experiments showed that the BCG vaccine containing this dual safety switch protects the animals against TB comparable to a standard BCG vaccination but has the added benefit of faster elimination and safety, even for mice that were immunocompromised. ... Trending News. Scientists Unveil the Cosmic Conveyor Belt: The Epic Voyage of Carbon ...
Self-destructing vaccine offers enhanced protection against ...
20 hours ago · Bacillus Calmette-Guérin (BCG) vaccine—named for its developers—contains inactivated mycobacteria that infect cattle and remains the only vaccination strategy against the infection in humans.
A BCG kill switch strain protects against - Nature
1 day ago · Bacille Calmette–Guérin (BCG) is a live Mycobacterium bovis strain that was attenuated by serial passaging and remains the only tuberculosis (TB) vaccine approved for human use. BCG protects ...
Pfizer's Bladder Cancer Therapy Meets Main Goal in Late-Stage …
18 hours ago · The antibody treatment, sasanlimab, in combination with Bacillus Calmette-Guérin (BCG) vaccine met the main goal of the study in patients with high-risk non-muscle invasive bladder cancer (NMIBC ...
Team reveals why new tuberculosis vaccine induces a stronger, …
Jul 3, 2024 · Researchers from the Butantan Institute and collaborators are developing a more potent version of the BCG vaccine that protects against tuberculosis. While the conventional immunizer reduced...
High-dose intravenous BCG vaccination induces enhanced …
Jan 1, 2025 · Bacillus Calmette-Guerin (BCG) is administered to approximately 130 million children every year to protect against Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) (1–3).While intradermal BCG is the only licensed TB vaccine, it inadequately protects against pulmonary infection in adults ().Consequently, TB remains a leading driver of infectious disease–related ...
Century-old vaccine protects type 1 diabetics from ... - ScienceDaily
May 23, 2024 · In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis,...
Century-old Vaccine Protects Type 1 Diabetics from Infectious …
BOSTON– In new research investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.