A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.

When a physician’s own incidental finding sends her down a long and winding path to find answers, she finds herself overcome with worry — but also, eventually, a new appreciation for life.

Trainees’ paths to safe, independent practice are variable. Artificial intelligence could help accelerate implementation of competency-based medical education to support individualized development.

A 7-year-old boy was brought to a hospital with a 3-month history of cognitive deterioration and seizures. He had contracted measles at 7 months of age while living in an area where the infection is ...

A 91-year-old man was admitted to the hospital with weight loss, dyspnea, and eosinophilia. An anteroposterior chest radiograph obtained 2 months earlier showed bibasilar patchy opacities. A ...

This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.

A high-school wrestler presented with an itchy rash that had worsened despite topical antifungal and glucocorticoid treatment. A circular, scaly plaque with papules, nodules, and pustules was seen ...

During the 6-year period, 7901 deaths occurred. The leading cause of maternal death was unintentional drug overdose (1152 deaths; 5.2 deaths per 100,000 live births). Violence (defined as homicide or ...

To the Editor: In the POTCAST (Targeted Potassium Levels to Decrease Arrhythmia Burden in High-Risk Patients with Cardiovascular Diseases) trial, Jøns et al. (Nov. 20 issue) 1 found compelling ...

Standard or Extended Lymphadenectomy for Muscle-Invasive Bladder Cancer (N Engl J Med 2024;391:1206-1216). In the legend for Figure 2 (page 1213), the median follow-up should have been 6.1 years, r ...

Recent court decisions have treated statements in drug labels as evidence of patent infringement by generic-drug manufacturers. The Supreme Court has an opportunity to address this trend.

A 60-year-old man presented with a 15-day history of generalized weakness and right upper abdominal pain. Imaging studies revealed diffuse disruption of the hepatic architecture by hyperechoic nodules ...