Background: Because they have chronic airway inflammation, adults with asthma could have symptomatic exacerbation after exposure to second hand smoke (SHS). Surprisingly, data on the effects of SHS ...

Introduction Despite impressive progress in development of human pulmonary organoid models, majority of these models are comprised predominantly of epithelial cells, with just a few reporting presence ...

Background Efficient therapy and potential prophylaxis are confounded by current ignorance of the pathogenesis of airway remodelling and blockade in COPD. Objective To explore the role of the ...

Background Indwelling pleural catheters are an effective treatment option for patients with malignant pleural effusions. Despite their popularity, there remains a paucity of data on the patient ...

Background Coronary artery calcification is pathognomonic of coronary artery disease (CAD). Whether CAD in patients with COPD is linked to lung function, functional capacity and/or clinically relevant ...

The acute respiratory distress syndrome (ARDS) is characterised by pulmonary inflammation and increased pulmonary vascular permeability, which results in non-cardiogenic pulmonary oedema and ...

Both common and rare variants contribute to the genetic architecture of pulmonary fibrosis. Genome-wide association studies have identified common variants, or those with a minor allele frequency of ...

Abstract These guidelines have been replaced by 2010 Guideline On Radical Management Of Patients With Lung Cancer and NICE Lung Cancer Guideline CG121 2011 Superseded By 2010 Guideline On Radical ...

This paper updates the evidence base and key recommendations of the Health Education Authority (HEA) smoking cessation guidelines for health professionals published in Thorax in 1998. The strategy for ...

Background Advance care planning (ACP) supports patients in identifying and documenting their preferences and timely discussing them with their relatives and healthcare professionals (HCPs). Since the ...

BACKGROUND Patients with severe chronic obstructive pulmonary disease (COPD) have a poor quality of life and limited life expectancy. This study examined whether these patients were relatively ...

Background The lower airway microbiota in patients with chronic obstructive pulmonary disease (COPD) are likely altered compared with the microbiota in healthy individuals. Information on how the ...