Peroxisome biogenesis disorders are related to a spectrum of genetic diseases that range from severe Zellweger syndrome to milder infantile Refsum disease. Zellweger syndrome is characterised by ...

A man in his early 60s presented with dysphagia and odynophagia. He was diagnosed with squamous cell carcinoma of the oesophagus. During his hospital stay, he developed a productive cough and ...

We present a case of unilateral, secondary open-angle glaucoma due to an underlying diffuse iris melanoma. The patient was referred by his ophthalmologist with uncontrolled, elevated intraocular ...

Obstructive uropathy secondary to malignant ureteral strictures is rare, with carcinoma of the breast accounting for less ...

Thurner syndrome (MTS) is a clinicopathological condition where the left common iliac vein is compressed by the overlying right common iliac artery, potentially leading to deep vein thrombosis (DVT) ...

A 47-year-old man presented to our outpatient clinic, preoccupied with hoarding of digital pictures, which severely interfered with his daily functioning. He was formerly diagnosed with autism and ...

Here, we describe a rare case of drug-induced unilateral ciliary body effusion precipitated by topical brinzolamide, presenting acutely with pain, angle closure and myopic shift. Ciliary body effusion ...

Severe left-to-right shunting from combined traumatic tricuspid valve rupture and atrial septal defect: bridge to surgical repair using veno-venous ECMO (29 January, 2025) ...

Vertebrobasilar dolichoectasia (VBD) is a rare condition characterised by ectasia, elongation and tortuosity in the vertebrobasilar arteries. VBD prevalence ranges from 0.05% to 18%. A possible ...

Penile calciphylaxis is a rare but clinically challenging condition to manage. While multiple treatment options have been proposed, the underlying evidence is anecdotal, and the overall prognosis ...

1 Centre for Rheumatology and Connective Tissue Diseases, Royal Free Hospital, London, UK Selective immunoglobulin M deficiency (sIgMD) is an immunodeficiency with undefined pathogenesis and commonly ...

Heat stroke is characterised by hyperthermia and acute encephalopathy. We describe a rare case of classical heat stroke secondary to prolonged sauna use with multiorgan sequelae including seizures, ...