The Boston Red Sox (30-35) and New York Yankees (39-23) play the second game of their 3-game series Saturday. First pitch from Yankee Stadium is set for 7:35 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Red Sox vs. Yankees odds and make our expert MLB picks and predictions for the best bets.

The Boston Red Sox will meet the New York Yankees in the first of a three-game weekend series on Friday. New York (38-23) leads the American League East, while Boston (30-34) is fourth in the division.

Mayer’s home run is the lone positive for Boston so far in this game. The Sox trail 8-1 in the sixth inning. The Yankees pounded starter Walker Buehler for seven runs (five earned), seven hits, two homers and two walks in the first two innings.