HKEY-AI4AI-Atlas™ 1.0: HKeyBio Uses AI to Curate Autoimmune Model Datasets

HKeyBio is building HKEY-AI4AI-Atlas™ 1.0, its AI-Assisted Autoimmune Model Data Atlas. The internal capability-building initiative uses AI-assisted dataset curation, standardization and retrieval to ...
Le Lézard

HKEY-AI4AI-Atlastm 1.0: HKeyBio Uses AI to Curate Autoimmune Model Datasets

HKeyBio is building HKEY-AI4AI-Atlastm 1.0, its AI-Assisted Autoimmune Model Data Atlas. The internal capability-building initiative uses AI-assisted dataset curation, standardization and retrieval to ...

New Phase 1 Data Show VNA-318 Mechanism of Action Translates to Humans, Supporting Potential to Address Medical Needs of People with Neurodegenerative Diseases

Pharmacodynamic effects in the human brain and energy metabolism biomarker data presented at AAIC support further clinical development of VNA-318 ...
Le Lézard

NeuroTherapia to Present Phase 2a Alzheimer's Disease Clinical Data at the AAIC 2026 Conference in London, UK

NeuroTherapia, Inc., a clinical-stage company focused on developing oral therapies for neurodegenerative diseases, will be presenting data from its recently completed Phase 2a clinical trial in ...

Tvardi Therapeutics’ TTI-109 Phase 1 Study Confirms Prodrug Design, Improved Tolerability and Pharmacodynamic Evidence of STAT3 Target Engagement

TTI-109 delivered TTI-101-equivalent exposure with improved tolerability and meaningful reductions in disease-relevant STAT3-driven immune cell ...

Climb Bio Presents CLYM116 Initial Phase 1 Safety Data and Translational Modeling Results at European Renal Association (ERA) Congress 2026 Supporting Continued Development

Company to share additional CLYM116 clinical data and plans for further development at R&D Spotlight in late summer. Initiation of CLYM116 dosing in IgAN patients in Mabworks Phas ...
Scientific Research Publishing

Gibiansky, L., Gibiansky, E., Kakkar, T. and Ma, P. (2008) Approximations of the Target-Mediated Drug Disposition Model and Identifiability of Model Parameters. Journal of ...

ABSTRACT: In this paper, we study a three-dimensional target-mediated drug disposition model consisted of the drugs (ligands), targets (receptors) and drug-target (ligand-receptor) complexes. In this ...
C&EN

Predicting Δ-9-Tetrahydrocannabinol-Induced Psychoactive and Cognitive Effects: A PBPK–PD Approach to Quantifying Feeling High and Reduced Alertness

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. You are free to share(copy and redistribute) this ...