The firm is testing the EGFR inhibitor BH-30643 in EGFR-mutated NSLC and the CLK inhibitor in certain blood cancers.

Waskyra, developed by Fondazione Telethon, is the first gene therapy that the FDA has approved from a non-profit applicant.

Researchers also discussed access barriers at the meeting, and a survey found distance was a major hindrance to CAR-T ...

Patient drug sensitivity profiles were linked to their genomic mutation profiles and could provide prognostic and survival data.

NEW YORK – A gene therapy using lentiviral particles to generate CAR T cells inside multiple myeloma patients has shown the ability to eliminate the small number of cancer cells in the bone marrow ...

Writing in JAMA, regulators said randomized controlled trials with a survival or time-to-event endpoint would be expected for approval of a new CAR T-cell therapy.

A new analysis presented at ASH found Black AML patients were five years younger, on average, than White patients, and less ...

Researchers have given the gene therapy made at UManchester to two out of five planned patients in a Phase I/II trial, and ...

Data presented at ASH suggest that the CRISPR therapy could provide a one-time functional cure in children as young as 5 ...

The firm plans to seek accelerated approval from the FDA next year, while it launches a Phase III trial to support other regulatory applications.

An expert panel now recommends using certain personalized therapies in the frontline setting for older adults with FLT3- and IDH1-mutant disease.

Researchers at ASH shared Phase III data comparing the pre- and five-year post-treatment adjusted annualized bleeding rates, ...