A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.

This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.

A 7-year-old boy was brought to a hospital with a 3-month history of cognitive deterioration and seizures. He had contracted measles at 7 months of age while living in an area where the ...

When a physician’s own incidental finding sends her down a long and winding path to find answers, she finds herself overcome with worry — but also, eventually, a new appreciation for life.

A high-school wrestler presented with an itchy rash that had worsened despite topical antifungal and glucocorticoid treatment. A circular, scaly plaque with papules, nodules, and pustules was seen ...

Beyond being a rare federal program focused on stabilizing rural health care services, the Rural Health Transformation Program represents a vehicle for advancing the administration’s health priorities ...

Recent court decisions have treated statements in drug labels as evidence of patent infringement by generic-drug manufacturers. The Supreme Court has an opportunity to address this trend.

We conducted a trial involving the release of male A. aegypti mosquitoes infected with the wAlbB strain of wolbachia bacteria for the control of dengue in Singapore, a tropical city-state. In this ...

A 60-year-old man presented with a 15-day history of generalized weakness and right upper abdominal pain. Imaging studies revealed diffuse disruption of the hepatic architecture by hyperechoic nodules ...

To the Editor: We have several concerns with regard to the ASCENT-03 trial by Cortés et al. (Nov. 13 issue). 1 First is the use of physician’s choice in determining the chemotherapy regimen for the ...

It is widely accepted that incident cardiovascular events in persons with a history of major atherosclerotic cardiovascular disease are largely preventable. 1,2 Most cardiovascular risk can be ...