President Donald Trump on Sunday issued a stark warning to Iran against retaliating on U.S. targets in the Middle East while also predicting Israel and Iran would “soon” make a deal to end their escalating conflict.

While the U.S. insists it is not involved in strikes on Iran, American officials have confirmed military forces have been helping to intercept Iranian missiles fired at Israel.

Israel and Iran exchange missile attacks for a third day; nuclear sites hit, death tolls rise, airspace shut, U.S. warns Tehran against retaliation.

President Donald Trump rejected an Israeli plan in recent days to kill Iran's Supreme Leader Ayatollah Ali Khamenei, two U.S. officials told ABC News. The officials stated that Israel shared with the United States that they had a window to kill Iran's leader but the president was not on board with the plan.

Shapiro served as Deputy Assistant Secretary of Defense for the Middle East until January—charged with, among other things, considering scenarios in which tensions between Israel and Iran escalated into all-out war and preparing U.

The conflict, the most intense fighting between the two countries in decades, has been met in the United States with feelings of “frustration and helplessness,” as well as heartbreak.

With Israel’s strikes on the Iranian nuclear sites, Prime Minister Benjamin Netanyahu might have played the gamble of his life. Without US involvement, it appears highly improbable for Israel to destroy Iran’s nuclear capabilities — the main objective of the war.

BEIRUT — Iran and Israel traded air raids and ballistic missile barrages overnight and into the evening Sunday, with neither side showing any inclination to back down from an escalating grudge match between the two longtime enemies.

President Trump rejected an Israeli plan in recent days to kill Iran's Supreme Leader Ayatollah Ali Khamenei, a senior U.S. official told USA TODAY.

Experts suggest the U.S. has a strategic opportunity to leverage Iran's weakened position for a nuclear deal after Israel's targeted strikes on Iranian nuclear and military sites.