Background and objective Prior studies have suggested that patients with premature ventricular complexes (PVCs) may have an ...

Milestone articles have highlighted the frequency and types of statistical errors in research,1–5 yet fundamental errors ...

Legalisation of medical and recreational cannabis commerce is spreading around the world, associated with increased use1 and ...

Background Mobility limitation is prevalent in patients with heart failure (HF), but the dose-response relationship between ...

Background Emerging evidence suggests associations between air pollution, multimorbidity, and atrial fibrillation (AF), but their interplay remains unclear. We evaluated these relationships in a ...

There is a paucity of studies looking at the natural history of valvular heart disease (VHD) in exercising individuals, and exercise recommendations are largely based on expert consensus. All ...

Background Conflicting evidence surrounds the effect of dietary macronutrient intake (fat, carbohydrate and protein) on cardiovascular disease (CVD), particularly in women. Methods Women (aged 50–55 ...

Objective There is currently no medical treatment proven to limit abdominal aortic aneurysm (AAA) progression. The aim of this systematic review and meta-analysis was to pool data from previous ...

Objective To determine the harms of proprotein convertase subtilisin/kexin 9 (PCSK9) inhibitors in people who need lipid-lowering therapy. Methods This systematic review included randomised controlled ...

Introduction Bicuspid aortic valve (BAV) affects 1% of the general population. NOTCH1 was the first gene associated with BAV. The proportion of familial and sporadic BAV disease attributed to NOTCH1 ...