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Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs). What is ...

How does the CRISPR Down Syndrome breakthrough work to remove the extra chromosome 21? We are closer than ever to a world where a genetic condition affecting one in every 700 babies could be addressed ...

Each known chromosome 21 gene and predicted open reading frame (ORF), identified using MWG-Biotech's non-redundant proprietary database, is represented once in the array by a 40-nucleotide-long ...

Sanjeev S. Ranade, PhD, is an assistant professor in the Center for Cardiovascular and Muscular Diseases and Center for Data Science and Artificial Intelligence at Sanford Burnham Prebys. Three copies ...