Over the past decade, there has been a substantial rise in older adults who use drugs. Largely underrecognized, this shift in the user population raises urgent questions for healthcare systems: How ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

SALISBURY — Every year, around the holidays, families gather to celebrate glad tidings, but for those living with substance use disorders, the holidays can be everything but a celebration. Hayley ...

What is craving? Craving is a subjective experience of wanting to use a specific drug. Craving is a core symptom of drug addiction. A craving is distinguished from hunger in being an intense, directed ...

Substance use and substance use disorder differ by the frequency of use and the effect on a person’s life. Substance use disorder is a mental health condition. Substance use refers to using both legal ...

Ahead of the Curve: Should Alcohol Use Have a Trigger Warning? Drinking alcohol is prevalent in so many shows and movies—especially law dramas—but it rarely appears as a content or trigger warning ...

Addiction is an umbrella term that reflects qualities of substance use disorder, characterized by an inability to stop using a substance despite harmful consequences. However, addiction is not a ...

Research on the biological basis of addiction published in Biological Psychiatry uncovers the critical role that the HDAC5 enzyme plays in gene expression in the brain's epigenetic mechanisms that ...