Get the full 49ers Week 10 practice and media schedule ahead of their matchup vs. the Rams, including press conferences and practice times.

NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams and San Francisco 49ers.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Thursday Night Football schedule, TV channel, time, streaming information for San Francisco 49ers vs Los Angeles Rams NFL Week 5 game on Oct. 2, 2025.

Find single game tickets to the San Francisco 49ers vs. New York Giants NFL Week 9 matchup on Sunday, November 2, 2025 at MetLife Stadium.

Week 9 vs. Giants with three full practices and media sessions featuring Kyle Shanahan, Robert Saleh, and Klay Kubiak.

The New York Giants and San Francisco 49ers face off in Week 9 of the NFL regular season today. Here's where to watch and start time.

Let's update our NFL Power Rankings ahead of Week 10. Plus, we picked out critical games remaining on the schedule for every team.