Get the full 49ers Week 10 practice and media schedule ahead of their matchup vs. the Rams, including press conferences and practice times.

NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams and San Francisco 49ers.

The Niners were fresh off a roster revamp, saying goodbye to nearly 20 players in the offseason, 15 of whom landed deals elsewhere worth up to a maximum of $341.5 million. In their place, the 49ers leaned into their youth, with an 11-man draft class and a free agent group that had no marquee players.

Few would have expected the lowly New York Giants to be a matchup of particular importance for the San Francisco 49ers, but the stakes have heightened entering Sunday, columnist Ann Killion writes.

Find single game tickets to the San Francisco 49ers vs. New York Giants NFL Week 9 matchup on Sunday, November 2, 2025 at MetLife Stadium.

Get the full San Francisco 49ers practice and media schedule ahead of Week 8 vs. the Texans, including press conferences and practice times.

The New York Giants and San Francisco 49ers face off in Week 9 of the NFL regular season today. Here's where to watch and start time.