The sequencing phase of the human genome project is now near completion, but then what? An even harder challenge remains — to identify the structures and functions of all proteins encoded in the ...

Membrane proteins are crucial for numerous biological processes and serve as important drug targets. For decades, scientists ...

*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...

Protein microarrays are one aspect of highly automated, large-scale biological screening technologies, the other is nucleic acid arrays. As DNA arrays reveal their origin in Southern blotting ...

Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability. Researchers from the Bhogaraju Group at ...

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

As illustrated by Dr. Carl Borrebaeck, [4] of Lund University, Sweden, bioarrays may be based on proteins or on affinity reagents. Defined sets of proteins, such as autoantigens, are spotted on ...

Since their inception in 1995, DNA microarrays have become the icon of the genomics revolution. Everyone with any interest has become familiar with the images of precise rows and columns of colored ...

Important processes take place among the subunits of the molecules that make up our cells. Defects in these processes or distortions in the subunits can lead to serious diseases. In order to better ...

BOSTON--(BUSINESS WIRE)--Sengenics today announced the commercial launch of the i-Ome® Protein Array Kit. The i-Ome® Protein Array Kit contains slide-based, high density protein microarrays, comprised ...