Scientists at St. Jude Children's Research Hospital have created a database that provides updated predicted structures on a regular basis, ensuring scientists can work with the most current ...

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...

The tectonic shift that has occurred in structural and molecular biology thanks to the abundance of high-quality protein 3D structure models calls for a new outlook on protein structures as a source ...

Harnessing the power of AI, a research team at the MRC-University of Glasgow Center for Virus Research has launched Viro3D—the most comprehensive database of human and animal virus protein structure ...

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and ...

Slime mould Dictyostelium discoideum protein complex Q55DI5 (AF-0000000066503175), annotated as a transcription elongation factor. The single chain looked disordered, but modelling the homodimer ...

Chemical probes — potent, selective, cell-active small molecules targeting specific proteins — constitute some of the most impactful research tools in the life sciences arsenal, as evidenced by ...

Recently, SandboxAQ launched what it claims is the largest publicly available dataset of protein-ligand pairs with annotated experimental binding potency data. According to the company, the ...

As Biohub unveiled the next-generation ESM, AI tools designed to model protein biology, Northwestern University scientist Shana Kelley said the innovations will help write “the book of life.” A ...

Scientists have created a mega-database revealing how half a million different DNA mutations generate errors in proteins in humans. The researchers hope that the database will be used to develop new, ...

The acquisition of actionable, meaningful insights from multiplex immunoassays requires a robust, accurate pipeline for data analysis and interpretation. This is also key to gaining, identifying, and ...