Bacteriophages, or phages for short, are viruses that infect bacteria. Using phages therapeutically could be very useful in fighting antibiotic-resistant pathogens, but the molecular interactions ...

The astounding number of anti-phage defenses encoded by bacteria is countered by an elaborate set of phage counter-defenses, though their evolutionary origins are often unknown. Here, we report the ...

As the number of antibiotic-resistant infections continues to rise, scientists are looking to bacteriophages (“phages”), viruses that infect bacteria, as an approach to tackling antibiotic resistance.

Mycobacteriophages are a diverse group of viruses infecting Mycobacterium with substantial therapeutic potential. However, as this potential becomes realized, the molecular details of phage infection ...

As antibacterial resistance continues to render obsolete the use of some antibiotics, some have turned to bacteria-killing viruses to treat acute infections as well as some chronic illnesses. Graham ...

Researchers at the University of Southampton have used advanced imaging techniques to uncover how bacteria use a mechanism called Kiwa to defend themselves against phage viruses. Phages are seen as a ...

BioRxiv (2023) PubMed PMID: 37546940; PubMed Central PMCID: PMC10402079. The mammalian innate immune system uses cyclic GMP–AMP synthase (cGAS) to synthesize the cyclic dinucleotide 2′,3′-cGAMP during ...

From antibiotics to antibacterial wipes, humans have developed ways to battle the threats microbes pose to our health. But bacteria are also contending with their own biological threats. These threats ...

As the globe faces a rise in antibiotic-resistant bacteria – making traditional antibiotics ineffective – specific viruses could offer a solution. Viruses called bacteriophages, or phages, target ...

As antibacterial resistance continues to render obsolete the use of some antibiotics, some have turned to bacteria-killing viruses to treat acute infections as well as some chronic illnesses. Graham ...