In a recent study published in Nature Cell Biology, a team of researchers discovered that the elevated expression of lamin-associated polypeptide 1 (LAP1), an inner nuclear membrane protein, helps ...

Tiny pores in the cell nucleus play an essential role for healthy aging by protecting and preserving the genetic material. A team from the Department of Theoretical Biophysics at the Max Planck ...

Nuclear membrane rupture is a physiological response to multiple in vivo processes, such as cell migration, that can cause extensive genome instability and upregulate invasive and inflammatory ...

Each cell contains well-defined compartments, each of which has a specific function. The nuclear envelope, for example, is a highly regulated membrane barrier that separates the nucleus from the ...

Cellular senescence is a state where cells permanently exit the cell cycle after a finite number of divisions, while maintaining metabolic activity. This phenomenon, initially described by Leonard ...