Jamie-Lynn Sigler saw what she believed was a sign from James Van Der Beek following his death last month. “I am mourning ...

Jamie-Lynn Sigler, who lives with multiple sclerosis, co-starred in an episode of Grey's Anatomy as a doctor with MS Sigler, 44, says that the role was created specifically for her — and for the first ...

Jamie-Lynn Sigler is opening up about how her multiple sclerosis (MS) battle played a role in her decision not to have a third baby with husband Cutter Dykstra. Sigler, 44, answered a fan’s question ...

Former "Sopranos" star Jamie-Lynn Sigler, a Jericho native who in 2016 revealed she had been battling MS for 15 years, will play a doctor with that disease in the Jan. 15 episode of ABC’s long-running ...

Spoiler alert! This story discusses the January 15 episode of Grey’s Anatomy, “Heavy on Me,” which is available to stream with a Hulu subscription. While much of the Grey’s Anatomy Season 22 fall ...

What happens when Meadow Soprano gets together with Jen Harding? We'll have to wait for Hollywood to come up with the script for that one, but you can witness firsthand the real-life relationship ...

Jamie-Lynn Sigler opened up about getting emotional filming her guest stint on Grey’s Anatomy amid her battle with multiple sclerosis. “Prior to this [opportunity], I was always trying to say, ‘We can ...

Jamie-Lynn Sigler teared up remembering hiding her MS for years while now playing a character with the disease on “Grey’s Anatomy.” While talking to ABC News’ Kelley Carter on “Good Morning America,” ...

Jamie-Lynn Sigler says her first role playing a character living openly with multiple sclerosis felt "divinely orchestrated." Sigler, who was diagnosed with MS more than two decades ago, guest starred ...