Add Yahoo as a preferred source to see more of our stories on Google. "Those were the hardest days I've ever had in my entire life," Sigler, 43, tells PEOPLE. "It was probably the most helpless I've ...

Jamie-Lynn Sigler, who lives with multiple sclerosis, co-starred in an episode of Grey's Anatomy as a doctor with MS Sigler, 44, says that the role was created specifically for her — and for the first ...

Jamie-Lynn Sigler formed a close bond with fellow actor Christina Applegate over their shared experience with MS. But their ...

Former "Sopranos" star Jamie-Lynn Sigler, a Jericho native who in 2016 revealed she had been battling MS for 15 years, will play a doctor with that disease in the Jan. 15 episode of ABC’s long-running ...

Jamie-Lynn Sigler teared up remembering hiding her MS for years while now playing a character with the disease on “Grey’s Anatomy.” While talking to ABC News’ Kelley Carter on “Good Morning America,” ...

Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive look at the March 23 episode of the game show Jamie-Lynn Sigler is going up ...

Who better to pronounce you husband and husband than your two best friends? Jamie-Lynn Sigler got ordained on Monday, and the 33-year-old Sopranos alum will be officiating Lance Bass and Michael ...

Jamie-Lynn Sigler has learned to live with pain since being diagnosed with multiple sclerosis when she was 20 — but nothing prepared her for the kind of anguish she faced last summer when her ...

After a three-year break from television, The Sopranos actor Jamie-Lynn Sigler is returning to the small screen in an important new guest role on ABC’s Grey’s Anatomy. According to Deadline, Sigler ...

'Deadline' reported that the role was created for Sigler, who was diagnosed with MS in 2002 Gary Miller/Getty Images Jamie-Lynn Sigler is joining the Grey's Anatomy cast! The actress, 44, revealed to ...