ZyVersa Therapeutics (ZVSA) highlights data from an article published in the peer-reviewed International Journal of Nanomedicine titled Small Intestinal Endocrine Cell Derived Exosomal ACE2 Protects ...

A joint effort involving research teams from Vanderbilt University Medical Center (VUMC) and the University of Michigan has linked the activities of a regulatory gene network and functional defects in ...

Researchers published the study covered in this summary on researchsquare.com as a preprint that has not yet been peer reviewed. Higher 25(OH)D levels associated with better homeostasis between ...

Type 2 diabetes (T2DM) is a systematic multi-organ metabolic disease, which is characterized by dynamic interplay among different organs. Pancreatic islet-liver axis is closely associated with normal ...

Long-term Western diet impairs islet blood vessel function and insulin transport even after diet reversal and weight loss, according to a new study from researchers at Karolinska Institutet. A new ...

The currently approved islet-transplant method infuses islets into a vein in the liver. This invasive procedure requires the long-term use of immune-suppressing drugs to prevent islet rejection, ...

The main cause of all forms of diabetes is pancreatic beta-cell dysfunction. Beta cells, found in the pancreatic islets, store and release insulin. Decades of research with animal and cellular models ...

Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression.

Melton pioneered the differentiation of insulin-producing beta cells from human stem cells, giving Alvarez-Dominguez unparalleled training under one of the field’s founders. He also knew something ...

In a recent study published in Nature Communications, researchers used a murine model to demonstrate that functional excision of murine phosphatidylinositol transfer protein alpha (PITPNA) impaired ...