The US Food and Drug Administration (FDA) is more likely to approve drugs with an orphan designation that were indicated for ...

Reporting on the real-world utilization of reference rituximab and its biosimilars can help show prescribing habits and reveal cost-saving opportunities. Objectives: Limited data exist on the adoption ...

The Orphan Drug Act of 1983 was enacted to provide financial incentives to stimulate drug development for rare diseases. In recent years, concerns have been raised regarding these orphan drugs, ...

During the 6-year period, 199 new indications for solid tumors were approved by the FDA; 138 (69.3%) were also approved by EMA and 124 (62.3%) by ANVISA. Discrepancies between approved labels and the ...

Uterine artery embolization (UAE) is a technique used by interventional radiology specialists. It was introduced several decades ago for the treatment of massive uterine hemorrhages due to various ...

We analysed the past 20 years of drug project history with the aim of understanding more about how the pharmaceutical industry has been performing with regard to therapeutic mechanisms and their ...

Outcomes Following GD2-Directed Postconsolidation Therapy for Neuroblastoma After Cessation of Random Assignment on ANBL0032: A Report From the Children's Oncology Group Authors retain all rights in ...