LA JOLLA, CA—Inside every human cell, proteins are constantly being tagged with small chemical modifications after they’re produced. Known as post-translational modifications, or PTMs, these can ...

When multiple drugs are taken simultaneously, the activity and effectiveness of one drug can be affected by another substance, usually another drug. Drug interactions are categorized into synergism ...

Traditional drug discovery and development involves several stages to identify a new drug 1. While these steps are crucial for discovering new treatments, the process is often time-consuming, ...

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and ...

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Researchers capture first-of-its-kind video of dynein–Lis1 protein interaction, supporting future drug development for neurological disorders. Our cells rely on microscopic highways and specialized ...

It's one thing to design a pharmaceutical drug. It's another to know if and why it actually works; not on paper or in a computer model, but inside the chaotic world of living systems, where proteins ...