Cellular senescence is a hallmark of age-related disorders, including cancer, in which senescence contributes to tumor progression and treatment resistance. Targeting senescent cells therapeutically ...

Hartono and colleagues report a non-invasive strategy that uses urine to monitor senescence and the effect of therapies that eliminate senescent cells. Given the increasingly acknowledged role of ...

A study in Scientific Reports evaluated a photoacoustic polydopamine-indocyanine green (PDA-ICG) nanoprobe for detecting senescent cells. Senescent cells play a role in tumor progression and ...

Kidney fibrosis, a common endpoint of chronic kidney disease (CKD), is strongly linked to aging, with cellular senescence emerging as a key driver in its pathogenesis. This overview synthesizes ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

Cellular senescence is commonly defined as a state characterized by permanent cell cycle arrest in the absence of cell death, in which cells have altered function. While cellular senescence has been ...

What if a process we associate with aging actually helps the body heal? A study led by Mikolaj Ogrodnik, LBI Trauma, published in Nature Cell Biology, shows that cells enter a state of senescence ...

A new meeting report was published in Volume 17, Issue 12 of Aging-US on December 23, 2025, titled "Cellular senescence meets infection: highlights from the 10th annual International Cell Senescence ...