The DNA in the cell nuclei of higher organisms is tightly coiled around protein complexes called nucleosomes, which repress gene expression. Researchers in Germany have now developed a model that ...

An imaging method that reveals a much more diverse and flexible DNA-protein chromatin chain than previously thought has now been developed by researchers. The result suggests a nimbler structure to ...

Eukaryotic genome stability relies on the presence of telomeres, specialized protein–DNA complexes that compose the very ends of the linear chromosomes 1. Telomeres form protective caps at the ends of ...

Scientists have created an unprecedented 3-dimensional structural model of a key molecular "machine" known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and ...

In both physics and chemistry, the mesoscopic scale refers to the length scale on which the properties of a material or phenomenon can be studied, without entering into a discussion about the behavior ...

UC Davis researchers have confirmed a central idea about chromosome repair, more than a quarter century after it was first proposed. The finding is important to scientists who seek to understand DNA ...

British scientist Rosalind Franklin was “an equal contributor” in the discovery of DNA structure and not a “victim”, according to scientists. Matthew Cobb, a professor of zoology at the University of ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in ...

Watson and Crick’s landmark paper, published in Nature in 1953, included only a cursory acknowledgment of Franklin’s work. The Nobel Prize followed nine years later—awarded solely to the men. Franklin ...