New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.

Australian researchers have discovered that the TAK1 gene helps cancer cells survive attack from the immune system, revealing ...

Combination therapy with nogapendekin alfa inbakicept and BCG achieved a 3-year DSS rate of 96% in BCG-unresponsive NMIBC ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...

Background Metabolic dysfunction-associated steatohepatitis-related hepatocellular carcinoma (MASH-HCC) has been reported to be less responsive to immune checkpoint inhibitors, which may be associated ...

Immune protection fades with time, and much of that decline traces back to the thymus. This small organ, located in front of the heart, trains new T cells and releases signals that help them survive.

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a ...

Dietary iron deficiency in mice alters lung T cell activation during influenza infection and leads to memory T cells that are ...