Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies When using antibodies in research or ...

Researchers have developed a novel antibody-based enzyme switch that converts antibody–antigen binding into enzyme activity, paving the way from detection via bioluminescence to the control of ...

Purity, aggregation state, and target binding are critical quality requirements that need to be monitored throughout the antibody development cycle as they impact product efficacy and safety. Yet, ...

Antibody humanization involves modifying antibodies from non-human sources, such as mice, to decrease their immunogenicity in human applications. While mouse monoclonal antibodies are specific, they ...

This study introduces the Multidimensional Antiviral Antibody Database (MAAD), a comprehensive and standardized platform integrating sequence ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Antibodies, also known as immunoglobulins, are specialized proteins produced by the immune system to identify and neutralize foreign invaders, such as viruses, bacteria, and other pathogens. They are ...

Immunoassays are measurement procedures that use immune-based reagents to generate a detectable signal, allowing scientists to quantify biological processes. Scientists perform immunoassays to measure ...

IHC has become an indispensable ancillary technique used in anatomic pathology and basic research laboratories across the globe. 12 Pathologists routinely use IHC to aid in the diagnosis and prognosis ...

As cell therapies are increasingly integrated into conventional cancer treatment strategies, attention has turned to addressing challenges in production and quality control that hinder cell therapy ...