Directly after re-exposure to these cues, AMPA receptor subunits GluR2 and GluR3 and NMDA receptor subtype 2B were downregulated in synaptic membranes of the medial prefrontal cortex, and clathrin ...

They showed that these stimuli also decreased AMPA receptor-associated GSK3β activity ... an effect that lasted up to 1 hour after LTP induction. Blocking NMDA receptor activity abolished ...

Introduction Major depressive disorder (MDD) is a leading cause of disability worldwide, with a significant proportion of patients (10-20%) progressing to treatment-resistant depression (TRD). TRD is ...